From Ducan Epping's site:
http://www.yellow-bricks.com/srm-faq/
(and admin guide)

Can I change the IP information for the SRM server?
I would like to change the IP info for the SRM server once it is installed. Is this safe or is there a specific way to do this without issues? When changing the IP info for the SRM server, or if the credentials (account or password) need to be changed you will need to use a special utility to accomplish either of these changes. Once the change is done you will also need to pair the two sites again. You can find detailed info on how to do this on page 85, in Appendix C of the SRM Admin Guide.