http://www.vmware.com/support/developer/vcli/

You can run most vSphere CLI commands against ESX/ESXi 4.0 and ESX/ESXi 3.5 Update 2 and later. When you run vSphere CLI 4.0 against ESX/ESXi 3.5 Update 2 and later, only the commands and command options supported by Remote CLI 3.5 Update 2 are supported.

See http://www.vmware.com/support/developer/vcli/vcli40/vcli_40_relnotes.html

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vCLI does support both ESX(i) 3.5 and 4.0, there may be some changes in the script options but they should work in general. There are a few that are 3.5 specific which will end with 35 such as (esxcfg-mpath35 and vihostupdate35). You will not be able to manage ESX(i) 4.0 with RCLI, you'll need to make sure you're using vCLI.

I would definitely test it out before using in production but for the most part it should be fully compatible.

=========================================================================
William Lam
VMware vExpert 2009
VMware ESX/ESXi scripts and resources at: http://engineering.ucsb.edu/~duonglt/vmware/
vGhetto Script Repository
VMware Code Central - Scripts/Sample code for Developers and Administrators
http://twitter.com/lamw



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