Check the following thread:
http://communities.vmware.com/thread/140931?start=45&tstart=0
Here robertl30 states:
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"Good news. VMware came back with some good info on how to better work around the issue where we see large VMs (over 4GB RAM) that have very long restart times. At first they had us turn off Page Sharing at the ESX host. But it turns out we can disable this feature on a per-VM basis.
I added the Advanced VM setting "
sched.mem.pshare.enable" option to
False (Edit Settings, Options, Advanced, General, Configuration Parameters, Add Row). I then moved the VMs to production hosts that did not have the Page Sharing feature disabled. I restarted each server twice and the performance was normal.
VMware also provided guidance on how to determine the effectiveness of Page Sharing in general. The tool to use is in the ESX CLI and is called "esxtop". Press M to bring up the memory page and observe data on the PSHARE row.
VMware also is stating that they are still looking at engineering a fix for ESX 3.5, but that the problem is already fully resolved in vSphere 4."
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I tried these steps and they solved the problems I had with x64 on "certain" hardware.